Clinical Trials
Active and recruiting trials in prosthetic valves and structural heart
50 trials
The Nordic Aortic Valve Intervention TrialActive Not Recruiting
NCT: NCT01057173Sponsor: Rigshospitalet, DenmarkEnrollment: 280Completion: Apr 2014
Prolonged Continuous ECG Monitoring Prior to Transcatheter Aortic Valve ImplantationActive Not Recruiting
NCT: NCT03561805Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de QuebecEnrollment: 106Completion: Jan 2020
PARTNER 3 Trial: Safety and Effectiveness of the SAPIEN 3 Transcatheter Heart Valve in Low Risk Patients With Aortic StenosisActive Not Recruiting
NCT: NCT02675114Sponsor: Edwards LifesciencesEnrollment: 1,000Completion: Nov 2020
Randomized Trial of the Neochord DS1000 System Versus Open Surgical RepairActive Not Recruiting
NCT: NCT02803957Sponsor: NeoChordEnrollment: 585Completion: Jan 2021
Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk PatientsActive Not Recruiting
NCT: NCT02701283Sponsor: Medtronic CardiovascularEnrollment: 2,223Completion: Apr 2021
SAPIEN 3 Ultra System PMCFActive Not Recruiting
NCT: NCT04555967Sponsor: Edwards LifesciencesEnrollment: 200Completion: Sep 2021
Assessment of Paravalvular Leak After TAVI by Hemodynamic Measurements and Cardiac MRIActive Not Recruiting
NCT: NCT04281771Sponsor: Radboud University Medical CenterEnrollment: 92Completion: Nov 2021
A Feasibility Study of the Millipede Transcatheter Annuloplasty Ring System in Patients With Functional Mitral RegurgitationActive Not Recruiting
NCT: NCT04147884Sponsor: Boston Scientific CorporationEnrollment: 4Completion: Dec 2021
Assessment of Arrhythmic BuRdEn With Post-ProCedural COntinuous ElectRocarDiographic Monitoring in Patients Undergoing Transcatheter Aortic Valve Implantation: The RECORD StudyActive Not Recruiting
NCT: NCT04298593Sponsor: Institut universitaire de cardiologie et de pneumologie de Québec, University LavalEnrollment: 200Completion: Dec 2021
ACURATE neo2™ Post Market Clinical Follow up StudyActive Not Recruiting
NCT: NCT04655248Sponsor: Boston Scientific CorporationEnrollment: 250Completion: Mar 2022
MitraClip EXPAND G4 StudyActive Not Recruiting
NCT: NCT04177394Sponsor: Abbott Medical DevicesEnrollment: 1,164Completion: May 2022
THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation StudyActive Not Recruiting
NCT: NCT02732704Sponsor: JenaValve Technology, Inc.Enrollment: 100Completion: Aug 2022
TRILUMINATE Pivotal TrialActive Not Recruiting
NCT: NCT03904147Sponsor: Abbott Medical DevicesEnrollment: 572Completion: Nov 2022
SQ-Kyrin-T First-in-man Feasibility StudyActive Not Recruiting
NCT: NCT06605313Sponsor: Shanghai Shenqi Medical Technology Co., LtdEnrollment: 12Completion: Dec 2022
Portico Next Generation Approval StudyActive Not Recruiting
NCT: NCT04011722Sponsor: Abbott Medical DevicesEnrollment: 333Completion: Jan 2023
Transcatheter Aortic Valve Replacement to UNload the Left Ventricle in Patients With ADvanced Heart Failure (TAVR UNLOAD)Active Not Recruiting
NCT: NCT02661451Sponsor: Cardiovascular Research Foundation, New YorkEnrollment: 178Completion: Feb 2023
Evolut PRO China Clinical StudyActive Not Recruiting
NCT: NCT04982588Sponsor: Medtronic CardiovascularEnrollment: 52Completion: Mar 2023
Transcatheter Repair of Tricuspid Regurgitation With Edwards PASCAL Transcatheter Valve Repair SystemActive Not Recruiting
NCT: NCT04614402Sponsor: Edwards LifesciencesEnrollment: 300Completion: Apr 2023
PrizValve® Transcatheter Aortic Valve Replacement StudyActive Not Recruiting
NCT: NCT04836897Sponsor: Shanghai NewMed Medical Co., Ltd.Enrollment: 120Completion: Jun 2023
Innoventric Trillium™ Stent Graft First-in-Human (FIH) StudyActive Not Recruiting
NCT: NCT04289870Sponsor: Innoventric LTDEnrollment: 20Completion: Jul 2023
NCT: NCT03383445Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de QuebecEnrollment: 300Completion: Oct 2023
SMall Annuli Randomized To Evolut™ or SAPIEN™ TrialActive Not Recruiting
NCT: NCT04722250Sponsor: Medtronic CardiovascularEnrollment: 1,103Completion: Nov 2023
Safety and Effectiveness Study of SQ-Kyrin TMVr System for Functional Mitral RegurgitationActive Not Recruiting
NCT: NCT05988450Sponsor: Shanghai Shenqi Medical Technology Co., LtdEnrollment: 125Completion: Dec 2023
Use of DurAVR™ THV System in Subjects With Severe Aortic Stenosis: Early Feasibility StudyActive Not Recruiting
NCT: NCT05712161Sponsor: Anteris Technologies Ltd.Enrollment: 15Completion: Dec 2023
2019-06 TRISCEND StudyActive Not Recruiting
NCT: NCT04221490Sponsor: Edwards LifesciencesEnrollment: 228Completion: Jan 2024
Transfemoral Implant of Inovare® Transcatheter ValveActive Not Recruiting
NCT: NCT05531578Sponsor: Braile Biomedica Ind. Com. e Repr. Ltda.Enrollment: 60Completion: Feb 2024
EARLY TAVR: Evaluation of TAVR Compared to Surveillance for Patients With Asymptomatic Severe Aortic StenosisActive Not Recruiting
NCT: NCT03042104Sponsor: Edwards LifesciencesEnrollment: 901Completion: Mar 2024
Stress Aortic Valve Index for Assessing Risk in Aortic Valve Stenosis PatientsActive Not Recruiting
NCT: NCT04514250Sponsor: Catharina Ziekenhuis EindhovenEnrollment: 52Completion: Oct 2024
NVT ALLEGRA TAVI System TF in Failing Calcified Aortic Heart Valves in a Real-world Patient PopulationActive Not Recruiting
NCT: NCT03613246Sponsor: NVT GmbHEnrollment: 346Completion: Dec 2024
Age and Sex-Specific PREValence of AcqUirEd VALVular Heart DiseasEActive Not Recruiting
NCT: NCT05357404Sponsor: Cardiovascular Research Foundation, New YorkEnrollment: 2,870Completion: Jan 2025
Gender-specific Evaluation of Symptom Awareness in Female Versus Male Patients with Severe Aortic StenosisActive Not Recruiting
NCT: NCT06677528Sponsor: Heart and Diabetes Center North-Rhine WestfaliaEnrollment: 800Completion: Jun 2025
Telotristat Ethyl for the Treatment of Carcinoid Heart Disease in Patients With Metastatic Neuroendocrine TumorActive Not Recruiting
NCT: NCT04810091Sponsor: M.D. Anderson Cancer CenterEnrollment: 79Completion: Aug 2025
TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US)Active Not Recruiting
NCT: NCT06568003Sponsor: Jenscare Innovation Inc.Enrollment: 15Completion: Oct 2025
Balloon-Expandable Versus Self-expanding Transcatheter Heart Valve for Treatment of Symptomatic Native Aortic Valve Stenosis (BEST)Active Not Recruiting
NCT: NCT05454150Sponsor: University Hospital, LilleEnrollment: 1,960Completion: Oct 2025
Percutaneous Coronary Intervention Before Transcatheter Aortic Valve ImplantationActive Not Recruiting
NCT: NCT05078619Sponsor: UMC UtrechtEnrollment: 466Completion: Dec 2025
Siegel™ Transcatheter Aortic Valve Replacement System (TAVR) Early Feasibility StudyActive Not Recruiting
NCT: NCT06680427Sponsor: MiRusEnrollment: 30Completion: Dec 2025
TRISCEND II Pivotal TrialActive Not Recruiting
NCT: NCT04482062Sponsor: Edwards LifesciencesEnrollment: 864Completion: Dec 2025
Comparison of Left Bundle Branch Area Versus Right Ventricular Septal Pacing in Patients With High-degree Conduction Disease After Transcatheter Aortic Valve Replacement (Left Bundle BRAVE)Active Not Recruiting
NCT: NCT05541679Sponsor: Main Line HealthEnrollment: 46Completion: Dec 2025
Impact of TAVI on the Gut Microbiota and Its MetabolitesActive Not Recruiting
NCT: NCT07565077Sponsor: Insel Gruppe AG, University Hospital BernEnrollment: 40Completion: Feb 2026
The Use of ACURATE Neo 2 Valve in Patients With Symptomatic Aortic Valve StenosisActive Not Recruiting
NCT: NCT05847751Sponsor: Ceric SàrlEnrollment: 51Completion: Apr 2026
The Nordic Aortic Valve Intervention Trial 4 (NOTION-4)Active Not Recruiting
NCT: NCT06449469Sponsor: Rigshospitalet, DenmarkEnrollment: 352Completion: Apr 2026
Early Percutaneous Mitral Intervention in Asymptomatic Moderate Mitral StenosisActive Not Recruiting
NCT: NCT01406353Sponsor: Asan Medical CenterEnrollment: 167Completion: May 2026
Evaluation of Lomecel-B™ Injection in Patients With Hypoplastic Left Heart Syndrome (HLHS): A Phase IIb Clinical Trial.Active Not Recruiting
NCT: NCT04925024Sponsor: Longeveron Inc.Enrollment: 40Completion: Jun 2026
TRICuspid Intervention in Heart Failure TrialActive Not Recruiting
NCT: NCT04634266Sponsor: LMU KlinikumEnrollment: 360Completion: Jul 2026
DurAVR™ THV EU-EFSActive Not Recruiting
NCT: NCT06510855Sponsor: Anteris Technologies Ltd.Enrollment: 40Completion: Jul 2026
Early Safety and Clinical Efficacy of Mitral Allograft in Tricuspid SurgeryActive Not Recruiting
NCT: NCT06196684Sponsor: Chelyabinsk Regional Clinical HospitalEnrollment: 30Completion: Sep 2026
Paired-Ring Mitral Annuloplasty Ring Sizing DeviceActive Not Recruiting
NCT: NCT06965725Sponsor: Endeavor HealthEnrollment: 22Completion: Nov 2026
Evaluation of the Viability and Safety of Early Discharge Protocol After TAVI ImplantationActive Not Recruiting
NCT: NCT05758909Sponsor: Fundación EPICEnrollment: 585Completion: Dec 2026
Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk SurgeryActive Not Recruiting
NCT: NCT03271762Sponsor: Nantes University HospitalEnrollment: 330Completion: Dec 2026
Electrophysiological Outcomes After Transcatheter Aortic Valve ReplacementActive Not Recruiting
NCT: NCT07390513Sponsor: Chinese Academy of Medical Sciences, Fuwai HospitalEnrollment: 1,000Completion: Dec 2026